List of participating research groups
_____________________________________________________________________________
2008 Winter Meeting, Weil Cornell Medical College
February 29, 2007
Yarden Opatowsky, Pharmacology, Yale Univ
Activation of receptor tyrosine kinase Kit by Stem Cell Factor
Carlos Escalante, Struct & Chem Biol, Mt. Sinai
Structural and functional studies of AAV Rep proteins
Matt Bick, Molec Biophysics, Rockefeller University
How to switch off a histidine kinase: 2Å structure of KinB/Sda
Liang Tong, Columbia University
Structural Studies of Fatty Acid Metabolism and the Obesity Epidemic
Linda Nicholson, Physical Biochemistry, Cornell Univ
Pin1, a molecular timer in Alzheimer’s disease
Alex Shekhtman, Chemistry, SUNY Albany
In-vivo Biochemistry using NMR Spectroscopy
Charalampos Kalodimos, Chemistry, Rutgers Univ
Structural basis for assembly of large protein machineries by NMR
Da-Neng Wang, Struct Biol, NYU School of Medicine
LeuT-desipramine structure reveals how antidepressants work
Qinglian Liu, Biochem & Biophys, Columbia
Insights into Hsp70 chaperone from a structure of yeast Hsp110 Ssel
Holger Sondermann, Molecular Medicine, Cornell U
Regulation of the diguanylate cyclase response regulator WspR
James Love, NYCOMPS, NYSBC
High throuput membrane protein production at NYCOMPS
David Stokes, Struct Biol, NYU School of Medicine
Structure of an ATP-dependent copper pump by cryoEM
Michael Rout (Cellular and Struc Biol, Rockefeller Univ)
Structure, function and evolution of the nuclear pore complex
_____________________________________________________________________________
2007 Summer Meeting, New York Academy of Sciences
August 8, 2007
Erec Stebbins, Structural Microbiology, Rockefeller University
Structural Microbiology in Bacterial Pathogenesis
Jung-Hyun Min (Pavletich Lab), Structural Biology, Memorial Sloan Kettering Cancer Center
DNA-damage Recognition by Rad4 Nucleotide Excision Repair Protein
Hiro Furukawa, Cold Spring Harbor Laboratory
Structure and Function of NMDA receptors
Iban Ubarretxena, Struct & Chem Biol, Mt. Sinai School of Medicine
Structural and Functional Studies of Intramembrane Proteases
Chunyu Wang, Biology, Rensselaer Polytechnic Institute
Aβ40 Protects Nontoxic Aβ42 Monomer from Aggregation
Fabien Ferrage, CNRS & NYSBC
The Nuclear Overhauser Effect for Protein Structure and Dynamics
Boris Reva (Sander Lab), Computational Biology, Memorial Sloan Kettering Cancer Center
Assessing the Functional Consequences of Protein Mutations in Cancer
Tonya Silkov, Pharmacology, Columbia University
Structural Analysis of ANTH-ENTH-VHS Superfamily
Richard Bonneau, Biology, New York University
The Human Proteome Folding Project: Can Rosetta de novo Contribute
to Genome Annotation?
Gino Cingolani, SUNY Upstate Medical University
Architecture of Viral Cell Envelope Penetration Device
Greg Boel (Hunt Lab), Biological Sciences, Columbia University
From Transmembrane Transport to Translational Regulation
Steve Soisson, Merck
Structural Basis for Inhibition of Fatty Acid Synthesis by Platensimycin
Wayne Hendrickson, Biochemistry & Biophysics, Columbia University
Structure-based Design of HIV Entry Inhibitors
_____________________________________________________________________________
2007 Winter Meeting, City College of New York,
January 24, 2007
Tom Muir, Protein Chemistry, Rockefeller University
The Ins and Outs of K+ channels explored through synthesis
Jaclyn Greimann (Lima Lab), Structural Biology, Sloan Kettering Inst
The eukaryotic RNA exosome
Suvobrata Chakravarty (Zhou Lab), Mol. Physiol. & Biophys., Mt Sinai School of Medicine
Histone binding selectivity of bromodomains
Yingkai Zhang, Chemistry, New York University
Computer simulation of histone modifying enzymes
Juha Himanen (Nikolov Lab), Structural Biology, Sloan Kettering Institute
Eph receptor signaling
Alexei Soares, NSLS, Brookhaven National Laboratory
Automation program for macromolecular crystallography at NSLS
Ronald Koder, Physics, City College of New York
Oxygen binding & activation in a de novo designed hemoprotein
Erik Martinez-Hackert (Hendrickson's Lab), Biochemistry & Biophysics, Columbia
Recognition, folding & biogenesis by the chaperone trigger factor
Steve Almo, Physiology & Biophysics, Einstein College of Medicine
Stuctural biology of T-cell co-stimulation
Marc Allaire, NSLS, Brookhaven National Lab
Transient intermediates in the molecular machinery for nutrient uptake
Elena Yakubovskaya (Bogenhagen Lab), Pharmacology, SUNY Stony Brook
EM structure of human mitochondrial DNA poymerase
Larry Shapiro, Biochem. & Molec. Biophysics, Columbia
Cellular energy regulation by the AMP-activated protein kinase
_____________________________________________________________________________
2006 Summer Meeting, Cold Spring Harbor Laboratory,
July 19, 2006
Ranajeet Ghose, Chemistry, City College of New York
A molecular anchor for intramembrane proteolysis
Ying Huang (Xu Lab), Skirball Inst, NYU School of Medicine
Structural mechanisms of histone code recognition
Jayakrishnan Nandakumar (Lima Lab), Structural Biology, Sloan Kettering
Structures of RNA ligase intermediates elucidate
the catalytic mechanism
Scott Blanchard, Physiol & Biophys, Weill Medical College
Imaging protein synthesis using single-molecule FRET
Filippo Mancia, Bioch & Mol Biophys, Columbia Univ
Asymmetry in dimeric associations of the serotonin 2c receptor
Andrew Stewart (Jacobsen Lab), Physics, Stony Brook University
Diffraction microscopy: will it lead to crystallography without crystals?
Julio Fernandez, Biology, Columbia Univ
Force-dependent activity of thioredoxin at the level of single disulfides
Ann McDermott, Chemistry, Columbia Univ
Solid state NMR studies of membrane associated proteins
Matt Vetting (Blanchard Lab), Biochem, Einstein College of Medicine
The pentapeptide repeat protein fold and fluoroquinolone resistance
Giovanna Scapin, Medicinal Chemistry, Merck
1st & 2nd generation DP-4 inhibitors for treatment of type 2 diabetes
Carlos Simmerling, Chemistry, Stony Brook University
Conformational dynamics of HIV-1 protease
Eric Enemark (Joshua-Tor lab), Struct Biology, Cold Spring Harbor Lab
DNA translocation by a replicative hexameric helicase
Dinshaw Patel, Structural Biology, Sloan Kettering Cancer Center
Structural biology of riboswitches and the histone code
_____________________________________________________________________________
2006 Winter Meeting, Hunter College School for Health Sciences,
January 24, 2006
Art Palmer, Biochem & Mol Biophys, Columbia Univ
Folding of the villin headpiece domain
Olga Boudker, Physiol & Biophys, Weill Med College
Structural insights into the
mechanism of glutamate transporters
Alex Kentsis (Osman Lab), Physiol & Biophys,
Mt. Sinai
Protein stability calculations using
Monte Carlo and graph manifold learning
Huilin Li, Biology, Brookhaven National Laboratory
A tale of two protease complexes
Diana Murray, Microbiol & Immun, Weill Med
College
PTEN and membrane re-organization: A
computational perspective
Yang Shen (Tong Lab), Biology,
Columbia University
Novel mechanism for inhibition of
acetyl-CoA carboxylase by soraphen A
Rod MacKinnon, Neurobiol & Biophys,
Rockefeller
Voltage dependent potassium channels
David Eliezer, Biochemistry, Weill Med College
Structural properties of the
Alzheimer’s disease protein tau
Bob Callender, Biochem, Einstein
College of Medicine
Contribution of atomic and molecular
motion to enzymatic catalysis
Deepak Nair (Aggarwal Lab), Physiol & Biophys,
Mt. Sinai
Structural basis of lesion bypass by
DNA polymerase iota and REV1
Marta Filizola, Physiol & Biophys, Weill Med
College
Structural models and dynamics of
GPCR oligomers
Richard Gillilan, MacCHESS, Cornell University
New opportunities with Cornell’s
Energy Recovery Linac
Kakoli Mitra (Frank Lab), Comp Biol & Mol
Imaging, Wadsworth Ctr
Structure of E. coli
protein-conducting channel bound to translating ribosome
Seth Darst, Molecular Biophys, Rockefeller
University
Structural basis for transcription-coupled DNA repair in bacteria
_____________________________________________________________________________
2005 Summer Session, Cold Spring Harbor Lab, August 10, 2005
Chris Lima, Memorial Sloan Kettering Cancer Center
Insights into E3 ligase activity and SUMO conjugation
Junjie Hu, NYU School of Medicine
Structural Basis for phosphotyrosine
recognition by the SH2 domains of SH2B and APS
Brajesh K. Rai, Fisher Lab, Albert Einstein
College of Medicine
Multiple Mapping Method: A novel
approach to the sequence-to-structure alignment problem in comparative
protein structure modeling
How does it cut? Insights into the incision reactions during nucleotide excision repair
Ned Seeman, New York University
DNA: Not Merely the Secret of Life
Trials and tribulations in the
structure determination of CPSF 100
NSLS-II: The Future National
Synchrotron Light Source
Eric Greene, Columbia University
Slip sliding away: visualizing
one-dimensional diffusion of proteins on DNA
The hepatitis C virus autoprotease is
a dimeric cysteine protease with a composite active site
Allan Simpson, GE Healthcare Sweden
Increasing Throughput in Protein
Purification
Robert Spencer & Brian McKeever, Merck
Research Labs
Exploring Membrane Protein Structure
at Merck
Wayne Hendrickson, Columbia University P&S
Follicle Stimulation Hormone(FSH)
stimulation of its receptor
_____________________________________________________________________________
Fiftysecond Meeting, April 20, 2005
Benoit Roux, Weill Medical College of Cornell University:
Selectivity of the K+ Channel: The Importance of Protein
Flexibility
Moosa Mohammadi, NYU School of Medicine
Structural Basis for FGF Receptor
Activation: Implications in Development and Disease
John Berriman, New York Structural Biology Center
Molecular Portraits by Cryo-EM: Old
Puzzles in Rotavirus
_____________________________________________________________________________
Fiftyfirst Meeting. February 23, 2005
Steve Hubbard,New York University:
Structural studies of MuSK receptor tyrosine kinase
Aneel Aggarwal, Mount Sinai School of Medicine:
David Wah, Public Health Research Institute:
A Substrate-Delivery System for an Energy-Dependent Proteolytic
Machine
_____________________________________________________________________________
Fiftieth Meeting. December 15, 2004
Hermann Schindelin, Stony Brook University:
Gephyrin - A bridge between molybdenum cofactor biosynthesis and
neuroreceptor anchoring
Milton Werner, Rockefeller University:
In search of the mechanism of transcriptional transactivation
Scott Strobel, Yale University:
Crystal structure of a group I intron splicing intermediate
_____________________________________________________________________________
Fortyninth Meeting. October 6, 2004
Xiang-Peng Kong, Skirball Institute, NYU School of Medicine:
CryoEM studies of bladder epithelial membrane plaques: structural
and functional implications
Hernando Sosa, Albert Einstein College of Medicine:
Configuration of the Kinesin-Microtubule Interaction as Seen by
Fluorescence Polarization Microscopy
Qiu-Xing Jiang, Rockefeller University:
Single particle analysis of a voltage-gated potassium channel KvAP
in an open conformation
_____________________________________________________________________________
Fortyeighth Meeting. April 7, 2004
Dinshaw Patel, Memorial Sloan-Kettering Cancer Center:
Protein-RNA Recognition Events in RNA Interference
Caroline Kisker, Stony Brook University:
Lesion (in)tolerance reveals insights into DNA replication fidelity
Roberto Sanchez, Mount Sinai School of Medicine:
How good/bad are comparative models of protein structure?
_____________________________________________________________________________
Fortyseventh Meeting. February 4, 2004
Kathy Borden, Mount Sinai School of Medicine:
Accidental Drug Discovery: The antiviral Ribavirin directly inhibits
eIF4E through physical mimicry of the m7Gcap
David Stokes, Skirball Institute, New York University School of
Medicine:
Electron tomography of desmosomes
Bradford Graves, Hoffman - La Roche, Inc.:
If at first you don't succeed ...: The binding of small molecule
antagonists to Mdm2
_____________________________________________________________________________
Fortysixth Meeting. December 3, 2003
Aneel Aggarwal, Mount Sinai School of Medicine:
SAM I am: A new RNA Binding Motif
Ming-Ming Zhou, Mount Sinai School of Medicine:
Probing the Molecular Mechanisms of the RNA-induced Silencing Pathway
Leemor Joshua-Tor, Cold Spring Harbor Laboratory:
The PAZ domain of Argonaute2: siRNAs at RISC
_____________________________________________________________________________
Fortyfifth Meeting. October 1, 2003
Lawrence Shapiro, Columbia University:
Adipocyte-secreted hormones modulate insulin action
Marilyn Gunner, City College:
Ruth Stark, CUNY College of Staten Island:
NMR studies of Molecular Structure and Dynamics in Fatty
Acid-Binding Proteins
_____________________________________________________________________________
Fortyfourth Meeting. May 28, 2003
Mark Chance, Albert Einstein Center for Synchrotron Biosciences:
Visualizing the Ca+2 Dependent Activation of Gelsolin Using
Synchrotron Footprinting
Erec Stebbins, Rockefeller University:
Manipulation of the Host Cytoskeleton by SipA of Salmonella
Clay Bracken, Weill Medical College of Cornell University:
NMR studies of helix formation and the unfolded state
_____________________________________________________________________________
Fortythird Meeting. March 26, 2003
Milton Werner,Rockefeller University:
Rethinking the activation mechanism of tumor necrosis factor death
receptors
John Hunt, Columbia University:
Structural mechanics of the SecA translocation ATPase and the
'A-protein' paradigm
Benoit Roux, Weill Medical College of Cornell University:
Theoretical and Computational Models of Ion Channels
_____________________________________________________________________________
Fortysecond Meeting. February 12, 2003
Chris Lima,Weill Medical College of Cornell University:
Capping mRNA, structural insights into co-transcriptional mRNA
processing
Stephen Burley, Structural Genomix:
Structure-based discovery of human protein kinase inhibitors
Themis Lazaridis, City College of New York:
Modeling membrane proteins in an implicit membrane
_____________________________________________________________________________
Fortyfirst Meeting. November 6, 2002
Eric Gouaux, Columbia University:
Mechanisms for activation and desensitization of glutamate receptors
Andy Neuwald, Cold Spring Harbor Laboratory:
Canonical Ras, Rab, Rho and Ran GTPase structural features and Ran's
Cterminal and basic patch mechanism
Rui-Ming Xu, Cold Spring Harbor Laboratory:
Structural studies of transcription silencing
_____________________________________________________________________________
Fortieth Meeting. May 29, 2002
Fred Hughson, Princeton University:
Structural identification of a bacterial quorum-sensing signal
containing boron
Mark Girvin, Albert Einstein College of Medicine:
Solution NMR of membrane proteins
Carlos Simmerling, SUNY Stonybrook:
Simulation of biomolecular structure and dynamics on large clusters
of personal computers
_____________________________________________________________________________
Thirtyninth Meeting. March 6, 2002
Yigong Shi, Princeton University
Structural mechanism of Apaf-1-mediated apoptosis
Diana Murray, Weil Medical College, Cornell University
Electrostatic regulation of protein-membrane interactions in
subcellular
targeting: Insights from computational analysis
Stephen Burley, Rockefeller University and Structural GenomiX
X-ray structure of the NC2-TBP-DNA ternary complex
_____________________________________________________________________________
Thirtyeighth Meeting. January 10, 2002
An-Suei Yang, Columbia University
Local sequence codes for protein structures
Hermann Schindelin, SUNY Stony Brook
Mechanistic insights into ubiquitin activation from the crystal
structure of
a bacterial MoeB-MoaD complex
Dimitar Nikolov, Sloan-Kettering Institute
Structure of an Eph receptor/ephrin complex
_____________________________________________________________________________
Thirtyseventh Meeting. November 28, 2001
Benoit Roux, Weill Medical College of Cornell University
Michael Becker, Brookhaven National Laboratory
Christopher Lima, Weill Medical College of Cornell University
_____________________________________________________________________________
Thirtysixth Meeting. October 3, 2001
Barry Honig, Columbia University
Ming-Ming Zhou, Mount Sinai School of Medicine
Leemor Joshua-Tor, Cold Spring Harbor Laboratory
_____________________________________________________________________________
Thirtyfifth Meeting. May 30, 2001
Nick Tonks, Cold Spring Harbor Laboratory
From Structure to Function of Protein Tyrosine Phosphatases
Marilyn Gunner, City University of New York
Motifs for Stabilizing Charges in Proteins
Seth Darst, The Rockefeller University
Structural Studies of Prokaryotic Transcription
_____________________________________________________________________________
Thirtyfourth Meeting. March 7, 2001
Min Lu, Weill Medical College of Cornell University
HIV-1 Membrane Fusion and its Inhibition
Kathy Borden, Mount Sinai School of Medicine
Structure, Function of PHD fingers: Does this have a familiar RING?
Hao Wu, Weill Medical College of Cornell University
Structural Studies of Caspase Inhibition
_____________________________________________________________________________
Thirtythird Meeting. January 8, 2001
Dimitar Nikolov, Sloan Kettering Institute
Structural Studies of a Nucleotidylyltransferase as a Tool for in
vitro Combinatorial Biosynthesis of Libraries
Joachim Frank, The Wadsworth Center
The Ribosome in Motion - Conformational Changes Observed by
Three-Dimensional Cryo-EM
Stephen Burley, The Rockefeller University
Structural Genomics of Cholesterol Biosynthesis
_____________________________________________________________________________
Thirtysecond Meeting. November 29, 2000
Steven Smith, SUNY Stony Brook
Internal Packing of Helical Membrane Proteins
Burkhard Rost, Columbia University
John Kuriyan, Rockefeller University
Structural Analysis of DNA Polymerase Clamp Loading
_____________________________________________________________________________
Thirtyfirst Meeting. September 27, 2000
Barry Honig, Columbia University
Combining bioinformatics and biophysics to predict protein structure
and function
Daniel Wyss, Schering Plough Research Institute
Structure and dynamics of the hepatitis C virus protease and helicase
Liang Tong, Columbia University
Structural basis of signal transduction by toll/IL1-R domains
_____________________________________________________________________________
Thirtieth Meeting. May 17, 2000
MICHAEL ROSEN, Sloan-Kettering Cancer Institute
Regulation of the Wiskott-Aldrich Syndrome Protein
STEVAN HUBBARD, NYU Medical Center
Structural Basis of Fibroblast Growth Factor Receptor Activation
TAMAR SCHLICK, NYU
Molecular Dynamics Analysis of DNA TATA-box variants
_____________________________________________________________________________
Twentyninth Meeting. March 22, 2000
ANN McDERMOTT, Columbia University
NMR studies of biomolecules
LARRY SHAPIRO, Mount Sinai
Structure and function of the obesity-related protein, tubby
CHRIS LIMA, Weill Medical College of Cornell University
Proteolytic regulation in the SUMO/Smt3 pathway
_____________________________________________________________________________
Twentyeighth Meeting. January 19, 2000
MARK GIRVIN, Albert Einstein College of Medicine
How Proton Translocation Drives Rotation in the ATP Synthase
ANNA MARIE PYLE, Columbia University
A kinetic and structural framework for helicase activity in the
DexH/D proteins
STEWART SHUMAN, Sloan-Kettering Institute
Structure and mechanism of the mRNA capping apparatus
_____________________________________________________________________________
Twentyseventh Meeting. December 1, 1999
Seth Darst, Rockefeller University:
Title to be arranged
Caroline Kisker, SUNY, Stony Brook
Crystal structure of UvrB provides insight into the mechanism of
nucleotide excision repair
David Beveridge, Wesleyan University
Title to be arranged
_____________________________________________________________________________
Twentysixth Meeting. September 29, 1999
Terry Gaasterland, Rockefeller University:
Comparative Genomics
Ming-Ming Zhou, Mount Sinai School of Medicine:
Protein-Protein Interactions in Chromatin Remodeling
Dinshaw Patel, Sloan-Kettering Institute:
Adaptive Recognition by Nucleic Acid Aptamers
_____________________________________________________________________________
Twentyfifth Meeting. May 19, 1999
Mike Rosen (Sloan-Kettering Institute)
Aneel Aggarwal (Mt. Sinai School of Medicine)
Gaetano Montelione (Rutgers University)
_____________________________________________________________________________
Twentyfourth Meeting. March 24, 1999
Andrej Sali (Rockefeller University)
Hao Wu (Cornell University Medical College)
Ned Seeman (New York University)
_____________________________________________________________________________
Twentythird Meeting. January 20, 1999
Eric Gouaux (Columbia University)
Burkhard Rost (Columbia University)
Milton Werner (Rockefeller University)
_____________________________________________________________________________
Twentysecond Meeting. November 11, 1998
Rich Friesner (Columbia University)
Axel Brünger (Yale University)
Thierry Fischmann (Schering-Plough Research Institute)
_____________________________________________________________________________
Twentyfirst Meeting. September 9, 1998
Rod Mackinnon, Rockefeller University
Art Palmer, Columbia University
Maria-Luisa Tasayco, City College
_____________________________________________________________________________
Twentieth Meeting. May 27, 1998.
Tamar Schlick, NYU
Elena Conti, Rockefeller University (Kuriyan Lab)
Steve Almo , Albert Einstein College of Medicine
_____________________________________________________________________________
Nineteenth Meeting. March 25, 1998.
Yale Evening:
Mark Gerstein
Andrew Miranker
Paul Sigler
_____________________________________________________________________________
Eighteenth Meeting. January 7, 1998.
David Stokes, NYU Medical Center
Tom Sakmar, Rockefeller
Wayne Hendrickson, Columbia University
_____________________________________________________________________________
Seventeenth Meeting. November 5, 1997.
Stevan Hubbard, NYU Medical Center
Dinshaw Patel, Sloan-Kettering Institute
Ann McDermott, Columbia University
_____________________________________________________________________________
Sixteenth Meeting. September 24, 1997.
Stephen Burley, Rockefeller University
Barry Honig, Columbia University
Dixie Goss, Hunter College
_____________________________________________________________________________
Seventh Meeting. November 29, 1995.
Stephen Burley, Rockefeller University
Marilyn Gunner, City College, CUNY
Art Palmer, Columbia University
_____________________________________________________________________________
Sixth Meeting. September 27, 1995.
Nikola Pavletich, Sloan-Kettering Institute
Bob Callender, City College, CUNY
Barry Honig, Columbia University
_____________________________________________________________________________
Fifth Meeting. May 17, 1995.
Paula Fitzgerald, Merck Research Labs
?
Harel Weinstein, Mt. Sinai School of Medicine
_____________________________________________________________________________
Fourth Meeting. March 8, 1995.
Ann McDermott, Columbia University
Andrej Sali, Rockefeller University
Stephen Burley, Rockefeller University
_____________________________________________________________________________
Third Meeting. January 11, 1995.
Ruben Abagyan, NYU Medical Center
Wayne Hendrickson, Columbia University
Dinshaw Patel, Sloan-Kettering Institute
_____________________________________________________________________________
Second Meeting. November 15, 1994.
Rich Friesner, Columbia University
Ned Seeman, New York University
Giovanna Scapin, Albert Einstein College of Medicine
_____________________________________________________________________________
First Meeting. September 28, 1994.
Anthony Nicholls, Columbia University
Nikola Pavletich, Sloan-Kettering Institute
Brian Chait, Rockefeller University
